Ryuji Hamamoto Selected Research

Histone-Lysine N-Methyltransferase

11/2021	EHMT1 knockdown induces apoptosis and cell cycle arrest in lung cancer cells by increasing CDKN1A expression.
7/2017	Protein lysine methyltransferase SMYD3 is involved in tumorigenesis through regulation of HER2 homodimerization.
7/2016	WHSC1L1 drives cell cycle progression through transcriptional regulation of CDC6 and CDK2 in squamous cell carcinoma of the head and neck.
4/2016	Automethylation of SUV39H2, an oncogenic histone lysine methyltransferase, regulates its binding affinity to substrate proteins.
7/2012	Histone lysine methyltransferase SETD8 promotes carcinogenesis by deregulating PCNA expression.
10/2011	Histone lysine methyltransferase Wolf-Hirschhorn syndrome candidate 1 is involved in human carcinogenesis through regulation of the Wnt pathway.

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Ryuji Hamamoto Research Topics

Disease

56	Neoplasms (Cancer) 01/2022 - 10/2002
24	Carcinogenesis 12/2020 - 10/2002
8	Lung Neoplasms (Lung Cancer) 11/2021 - 03/2010
7	Hepatocellular Carcinoma (Hepatoma) 01/2022 - 06/2002
6	Urinary Bladder Neoplasms (Bladder Cancer) 11/2020 - 05/2011
4	Colorectal Neoplasms (Colorectal Cancer) 01/2022 - 02/2006
4	Uterine Cervical Neoplasms (Cancer of the Cervix) 03/2021 - 09/2019
4	Breast Neoplasms (Breast Cancer) 01/2019 - 02/2006
3	Carcinoma (Carcinomatosis) 11/2020 - 01/2019
3	Squamous Cell Carcinoma of Head and Neck 01/2020 - 07/2016
3	Wolf-Hirschhorn Syndrome 05/2019 - 10/2011
3	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 06/2017 - 05/2011
2	Endometrial Neoplasms (Endometrial Cancer) 05/2022 - 06/2017
2	Colonic Neoplasms (Colon Cancer) 01/2022 - 10/2002
2	COVID-19 09/2021 - 09/2021
2	Prostatic Neoplasms (Prostate Cancer) 01/2021 - 11/2019
2	Adenocarcinoma of Lung 01/2020 - 01/2019
2	Liver Neoplasms (Liver Cancer) 12/2019 - 12/2017
2	Inflammation (Inflammations) 02/2018 - 01/2018
2	Esophageal Squamous Cell Carcinoma 02/2018 - 01/2018
2	Stomach Neoplasms (Stomach Cancer) 07/2017 - 01/2017
1	Pulmonary Emphysema 08/2022
1	Emphysema 08/2022
1	Chronic Obstructive Pulmonary Disease (COPD) 08/2022
1	Endometrioid Carcinoma 05/2022
1	Infections 09/2021
1	Disease Susceptibility (Diathesis) 01/2021
1	Radiation Injuries (Radiation Sickness) 01/2021
1	Ependymoma 01/2021
1	Virus Diseases (Viral Diseases) 01/2020
1	Lower Urinary Tract Symptoms 11/2019
1	Melanoma (Melanoma, Malignant) 01/2019
1	Chromosomal Instability (Chromosome Stability) 01/2019
1	Small Cell Lung Carcinoma (Small Cell Lung Cancer) 06/2018
1	Squamous Cell Neoplasms (Squamous Cell Cancer) 02/2018
1	Hepatitis B 12/2017

Drug/Important Bio-Agent (IBA)

20	Proteins (Proteins, Gene)FDA Link 01/2021 - 04/2005
19	Histone MethyltransferasesIBA 11/2021 - 08/2004
16	Histones (Histone)IBA 12/2020 - 10/2005
12	Lysine (L-Lysine)FDA Link 12/2020 - 02/2011
9	Biological ProductsIBA 01/2020 - 04/2005
9	Complementary DNA (cDNA)IBA 08/2012 - 06/2002
7	Histone DemethylasesIBA 07/2015 - 03/2010
6	RNA (Ribonucleic Acid)IBA 01/2022 - 06/2017
6	Histone-Lysine N-MethyltransferaseIBA 11/2021 - 10/2011
6	Small Interfering RNA (siRNA)IBA 08/2012 - 02/2006
5	Pharmaceutical PreparationsIBA 01/2021 - 05/2011
5	Enhancer of Zeste Homolog 2 ProteinIBA 05/2019 - 07/2011
4	Biomarkers (Surrogate Marker)IBA 05/2022 - 05/2011
4	MethyltransferasesIBA 01/2022 - 02/2006
3	ChromatinIBA 10/2021 - 02/2011
3	DNA (Deoxyribonucleic Acid)IBA 01/2020 - 01/2017
3	Arginine (L-Arginine)FDA Link 11/2015 - 02/2011
3	EnzymesIBA 08/2015 - 08/2013
3	Bromodeoxyuridine (BrdU)IBA 08/2013 - 05/2011
2	Messenger RNA (mRNA)IBA 01/2022 - 01/2020
2	Iodine-125IBA 01/2021 - 11/2019
2	Epidermal Growth Factor (EGF)IBA 11/2020 - 01/2019
2	Proliferating Cell Nuclear Antigen (PCNA)IBA 01/2017 - 07/2012
2	Protein MethyltransferasesIBA 04/2016 - 08/2015
2	Aurora Kinase BIBA 11/2015 - 01/2012
1	1,2-Dipalmitoylphosphatidylcholine (Dipalmitoylphosphatidylcholine)IBA 08/2022
1	Surface-Active Agents (Surfactants)IBA 08/2022
1	1-Acylglycerophosphocholine O-Acyltransferase (1 Acylglycerophosphocholine O Acyltransferase)IBA 08/2022
1	Pancreatic Elastase (Elastase)IBA 08/2022
1	SmokeIBA 08/2022
1	Exonucleases (3' 5' Exonuclease)IBA 05/2022
1	Cell Adhesion MoleculesIBA 01/2022
1	PropionatesIBA 01/2022
1	Small Cytoplasmic RNAIBA 10/2021
1	TransposasesIBA 10/2021
1	Peptidyl-Dipeptidase A (Angiotensin Converting Enzyme)IBA 09/2021
1	COVID-19 VaccinesIBA 09/2021
1	GenieIBA 03/2021
1	NucleotidesIBA 01/2021
1	Transcription Factors (Transcription Factor)IBA 01/2021
1	Proteoglycans (Proteoglycan)IBA 11/2020
1	MicroRNAs (MicroRNA)IBA 01/2020
1	6-methyladenineIBA 01/2020
1	N-methyladenosineIBA 01/2020
1	LLY-507IBA 01/2019
1	CamptothecinIBA 01/2019
1	Poly(ADP-ribose) Polymerase InhibitorsIBA 01/2019
1	B7-H1 AntigenIBA 01/2019
1	Phenobarbital (Luminal)FDA Link 01/2019
1	C-Reactive ProteinIBA 02/2018
1	AlbuminsIBA 02/2018
1	AflatoxinsIBA 12/2017
1	CateninsIBA 08/2017
1	Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA 07/2017
1	GSK-2816126IBA 06/2017
1	Doxorubicin (Adriamycin)FDA LinkGeneric 06/2017

Therapy/Procedure

10	Therapeutics 09/2021 - 05/2011
2	Radiotherapy 01/2021 - 09/2019
2	Molecular Targeted Therapy 01/2020 - 12/2019
2	Aftercare (After-Treatment) 08/2017 - 08/2012
1	Precision Medicine 01/2021
1	Chemoradiotherapy 01/2021
1	Drug Therapy (Chemotherapy) 09/2019
1	Immunotherapy 01/2019